Schedule 13G/A

-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, POnJuvvevAKnRCSA8Oi0AFLXg08VMPYSuHFVF6vKTkzznZVfTsh2rx0amxDxLQWi 1ikY76pjBQjr2R7GD3HFfA== 0001193125-05-026666.txt : 20050211 0001193125-05-026666.hdr.sgml : 20050211 20050211135307 ACCESSION NUMBER: 0001193125-05-026666 CONFORMED SUBMISSION TYPE: SC 13G/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20050211 DATE AS OF CHANGE: 20050211 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: DURECT CORP CENTRAL INDEX KEY: 0001082038 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 943297098 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-60499 FILM NUMBER: 05597041 BUSINESS ADDRESS: STREET 1: 10240 BUBB RD CITY: CUPERTINO STATE: CA ZIP: 95014 BUSINESS PHONE: 4087771417 MAIL ADDRESS: STREET 1: 10240 BUBB ROAD CITY: CUPERTINO STATE: CA ZIP: 95014 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: BROWN JAMES E CENTRAL INDEX KEY: 0001134620 FILING VALUES: FORM TYPE: SC 13G/A BUSINESS ADDRESS: STREET 1: 10240 BUBB ROAD CITY: CUPERTINO STATE: CA ZIP: 95014 BUSINESS PHONE: 4087771419 MAIL ADDRESS: STREET 2: 10240 BUBB RD CITY: CUPERTINO STATE: CA ZIP: 95014 SC 13G/A 1 dsc13ga.htm SCHEDULE 13G/A Schedule 13G/A

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 4)*

DURECT Corporation

(Name of Issuer)

Common Stock

(Title of Class of Securities)

266605104

(CUSIP Number)

December 31, 2004

(Date of Event Which Requires Filing of This Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

¨ Rule 13d-1(b)

¨ Rule 13d-1(c)

x Rule 13d-1(d)

The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP No. 266605104


1.		Name of Reporting Persons I.R.S. Identification No(s). of above person(s) (entities only) JAMES E. BROWN
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) n/a (b) n/a
3.		SEC USE ONLY
4.		Citizenship or Place of Organization USA

Number of

Beneficially

Owned by

Each

Reporting

Person

With:

5. Sole Voting Power

N/A

6. Shared Voting Power

2,844,700

7. Sole Dispositive Power

N/A

8. Shared Dispositive Power

2,844,700


9.		Aggregate Amount Beneficially Owned by Each Reporting Person 2,844,700
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) N/A
11.		Percent of Class Represented by Amount in Row (9) 5.48%
12.		Type of Reporting Person (See Instructions) Individual (IN)

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Item 1.

(a)

Name of Company:

DURECT Corporation

(b)

Address of Person Filing:

10240 Bubb Road

Cupertino, CA 95014

Item 2.

(a)

Name of Person Filing:

James E. Brown

(b)

Address of Principal Business Office or, if none, Residence:

10240 Bubb Road

Cupertino, CA 95014

(c)

Citizenship:

USA

(d)

Title of Class of Securities:

Common Stock

(e)

CUSIP Number:

266605104

Item 3.

If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:

(a)

Broker or Dealer registered under Section 15 of the Act (15 U.S.C. 78o);

(b)

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

(c)

Insurance company as defined in section 3(a)19) of the Act (15 U.S.C. 78c);

(d)

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

(e)

An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

(f)

An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

(g)

A parent holding company or control person in accordance with §240.13d-1(b)(ii)(G);

(h)

A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j)

Group, in accordance with §240.13d-1(b)(1)(ii)(J)

Not Applicable

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Item 4.	Ownership Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

	(a)	Amount Beneficially Owned: 2,844,700

	(b)	Percent of Class: 5.48%

	(c)	Number of shares as to which the person has:

		(i)	Sole power to vote or to direct the vote N/A

		(ii)	Shared power to vote or to direct the vote 2,844,700

		(iii)	Sole power to dispose or to direct the disposition of N/A

		(iv)	Shared power to dispose or to direct the disposition of 2,844,700

Item 5.	Ownership of More than Five Percent on Behalf of Another Person If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ¨.

Item 6.	Ownership of More than Five Percent on Behalf of Another Person By operation of Community Property laws of the state of California, reporting persons Spouse has the shared right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities.

Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person. Not Applicable

Item 8.	Identification and Classification of Members of the Group Not Applicable

Item 9.	Notice of Dissolution of a Group Not Applicable

Item 10.	Certification Not Applicable

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SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

February 11, 2005

Date

/s/ James E. Brown

Signature

James E. Brown / President and CEO

Name

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